The Priory of St Pancras was the first Cluniac house in England and had one of the largest monastic churches in the country. It was set within an extensive walled and gated precinct laid out in a commanding location fronting the tidal shore-line at the head of the Ouse valley to the south of Lewes in the County of Sussex. The Priory had daughter houses, including Castle Acre Priory in Norfolk, and was endowed with churches and extensive holdings throughout England. In Lewes it had hospitiums dedicated to St James and to St Nicholas